TRAZADONE (Desyrel, Trittico) prolonged releaseis used to treat depression, anxiety, or a combination of depression and anxiety. Trazodone works by increasing your levels of serotonin and noradrenaline so you feel better. It can help if you're having problems like low mood, not sleeping (insomnia) and poor concentration.

USES

• Depression: Trazodone is commonly prescribed as an antidepressant for the treatment of major depressive disorder (MDD), though it is often used in combination with other medications for better results.
• Insomnia: Trazodone is frequently used off-label to treat insomnia, especially in individuals who also have depression or anxiety. At lower doses, it can help improve sleep quality.
• Anxiety Disorders: Trazodone may also be used to help manage anxiety symptoms in certain cases.
• Post-Traumatic Stress Disorder (PTSD): In some cases, trazodone is prescribed to manage symptoms of PTSD, particularly when insomnia or depression is involved.
• Chronic Pain Syndromes: Trazodone may also be used in chronic pain management as part of a broader treatment plan.

GUARANTEE & EXPIRY DATE
100% original from the Italian Aziende Chimiche Riunite Angelini Francesco S.p.A. All packs are air tight sealed and expire up to 04.2027.

DESCRIPTION
Trazodone is a serotonin antagonist and reuptake inhibitor (SARI) antidepressant. It works by balancing certain chemicals in the brain, mainly serotonin, which helps improve mood, sleep, and emotional stability.

• Mechanism of Action: Trazodone works by inhibiting the reuptake of serotonin and blocking certain serotonin receptors in the brain. This action increases serotonin availability, which helps alleviate symptoms of depression and anxiety.
• Sedative Effect: Due to its sedative properties, trazodone is often prescribed at lower doses for individuals with insomnia.
• Onset of Action: The antidepressant effect may take 2 to 4 weeks to become noticeable, whereas the sedative effects can be felt sooner.

Read further: https://en.wikipedia.org/wiki/Trazodone

PACKAGING & DOSAGE
Trazodone comes in tablets and is prolonged release format.
Active ingredient: trazodone hydrochloride 150 mg.
Excipients: sucrose (pressed sugar), carnauba wax, povidone K25 (polyvinylpyrrolidone), magnesium stearate.

For Depression:

• Adults: The typical initial dose for depression is 150 mg/day, divided into multiple doses (usually 2-3 times a day). The dose may be gradually increased, and the maximum daily dose can go up to 400 mg/day.
• The dosage is typically increased or adjusted based on the patient’s response to the medication.

For Insomnia:

• Adults: For sleep disturbances, 25–50 mg is often taken at bedtime, especially when used off-label for insomnia. The dose may be adjusted based on individual response.
• Elderly or Sensitive Individuals:
• A lower starting dose is typically recommended, often beginning at 25–50 mg at night.

For Anxiety and Chronic Pain:

• Trazodone may be prescribed in lower doses for anxiety and pain management. Dosage varies based on individual needs and the physician's recommendation.

SIDE EFFECTS

• Drowsiness or sedation (this is why it's often used for sleep problems)
• Dizziness or lightheadedness, especially when standing up quickly
• Dry mouth
• Headache

STORAGE
Trazodone should be stored at room temperature (typically 15–25°C or 59–77°F). Store in a dry place away from light, and children.

QUESTIONS?
Ask us any questions about Trazodone.