Cyproterone acetate (Androcur) - is an anti-androgen that is used in the treatment of severe acne, excessive hair growth, early puberty and prostate cancer. Cyproterone suppresses the actions of testosterone (and its metabolite dihydrotestosterone) on tissues. It acts by blocking androgen receptors which prevents androgens from binding to them and suppresses luteinizing hormone (which in turn reduces testosterone levels).
- Treatment of Androgen-Dependent Conditions
- Skin and Hair Conditions Such as Acne, Seborrhea, Excessive Hair Growth and Scalp Hair Loss
- Treat Prostate Cancer
- Reduce Sex Drive in Men With Paraphilias or Hypersexuality
- Useful for Suppressing the Testosterone Flares and to Control the Testosterone Levels
GUARANTEE & EXPIRY DATE
100% Original from the German Bayer GmbH. Manufacturer and product photo may vary.All packs are air tight sealed and expire up to 10.2026.
The direct antiandrogenic effect of cyproterone is blockage of the binding of dihydrotestosterone to the specific receptors in the prostatic carcinoma cell. In addition, cyproterone exerts a negative feed-back on the hypothalamo-pituitary axis, by inhibiting the secretion of luteinizing hormone resulting in diminished production of testicular testosterone.
PACKAGING & DOSAGE
Comes in the form of tablets for oral use.
- For the treatment of prostate cancer, a dose of 200-300 mg per day divided into 2-3 doses, long-term use.
- To reduce sexual activity: 100-200 mg per day usually within a few weeks to achieve a therapeutic effect. Then switch to maintenance dose at 50 mg. When treatment is discontinued, the drug should be discontinued gradually (25 mg per week).
- Women with menopause: a dose of 25-50 mg per day for 21 days, followed by a 1 week break. Patients with a removed uterus can be given the drug in the same doses without a break.
Cyproterone acetate tablets should be taken after meals with water (up to 100 ml).
Cyproterone acetate (CPA) is generally well-tolerated and has a mild side-effect profile regardless of dosage when it is used in combination with an estrogen in women. Side effects of CPA in general include hypogonadism (low sex-hormone levels) and associated symptoms such as demasculinization, sexual dysfunction, infertility, and osteoporosis (fragile bones); breast changes such as breast tenderness, breast enlargement, and gynecomastia (breasts in men); emotional changes such as fatigue and depression; and other side effects such as vitamin B12 deficiency, weak glucocorticoid effects, and elevated liver enzymes. Weight gain can occur with CPA when it is used at high doses. Some of the side effects of CPA can be improved or fully prevented if it is combined with an estrogen to prevent estrogen deficiency. Few quantitative data are available on many of the potential side effects of CPA. Pooled tolerability data for CPA is not available in the literature.
At very high doses in aged men with prostate cancer, CPA can cause cardiovascular side effects. Rarely, CPA can produce blood clots, liver toxicity (including hepatitis, liver failure, and liver cancer), excessively high prolactin levels, and certain benign brain tumors including meningiomas (tumors of the meninges) and prolactinomas (prolactin-secreting tumors of the pituitary gland). Upon discontinuation from high doses, CPA can produce adrenal insufficiency as a withdrawal effect.
The MHRA and FDA has not evaluated or endorsed this product. Please consult your physician prior to using this or any other nutritional supplements or medications.
Store in a dry place, up to 25C degrees.
Keep away from direct sunlight. Keep locked and away from children.
Ask us any questions about Cyproterone acetate.