AMANTREL (Amantadine) 100 mg/tab, 90 tabs/pack

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PK-MERTZ (Amantadine, Gocovri) is an antiviral medication that is used to fight RNA & DNA viruses. It is also taken for the treatment of Parkinson’s Disease and the symptoms that resemble the symptoms of Parkinson’s Disease such as stiffness, tremors, etc. Sometimes the preparation is appointed as a part of therapy Hepatitis С patients.


  • Improves the condition of a patient diagnosed with Parkinson’s syndrome, Parkinson’s disease.
  • Causes increased interest to the surrounding in Parkinson’s patients.
  • Causes psychic brightening in Parkinson’s patients.
  • Prevents influenza A.
  • Improves the condition of a patient with neuralgia in Herpes Zoster caused by the virus Varicella Zoster.

Generic from Indian Cipla. Expiry date up to 01.2026.

The active substance of PK-MERTZ is Amantadine Sulphate. The exact mode of action of Amantadine is not fully clear. Blocking glutamate NMDA receptors, the drug removes the stimulatory effect of cortical glutamate neurons in the neostriatum, which is observed when the patient doesn’t have sufficient dopamine. PK-Merz prevents the activity of NMDA-receptors in the neurons of the substantia nigra and doesn’t let destroy these neurons. The medical preparation also doesn’t let influenza A virus enter the cell, thus protecting the person from illness. After the medication is taken, it is entirely absorbed from the gastrointestinal tract. The maximum amount of the drug can be found in 5 hours after the intake. The excretion occurs mainly with urine.

The medication is taken orally in a single dose of 100-200 mg depending on the condition of the patient and the patient’s response to the treatment. The dose shouldn’t exceed 600 mg a day. The dosage should be adjusted by the doctor.

When the patient takes 200 mg a day, it’s possible to achieve a steady state after 4-7 days of therapy.

It is not allowed to take alcohol during therapy with PK-Merz. There are other substances as well that should not be taken during the treatment. The patients with epilepsy, prostate hypertrophy, narrow angle glaucoma, and allergic reaction to some of the components of the medication should not take the drug. Consult the doctor to avoid the side effects and negative consequences of the medication.

It is recommended to store the medicine in a dark place at a temperature not exceeding 25°C.

Ask us any questions about PK-MERTZ.


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