SODIUM THIOSULFATE is used in the treatment of cyanide poisoning. Other uses include topical treatment of ringworm and tinea versicolor, and treating some side effects of hemodialysis and chemotherapy.
USES
- Cyanide poisoning.
- Calciphylaxis treatment.
- Extravasation injury treatment.
- Fungal infections.
- Chemotherapy Extravasation.
GUARANTEE & EXPIRY DATE
100% original from various Russian pharmaceutical manufacturers. Product photo may vary. All packs are air tight sealed and expire up to 02.2029.
DESCRIPTION
Sodium thiosulfate is an inorganic salt known for its ability to neutralize certain toxic substances. It is odorless, colorless, and highly soluble in water. In medicine, it works as a detoxifying agent by converting harmful compounds into less toxic or more easily excretable forms. It is often administered intravenously, orally, or topically, depending on the condition being treated.
In the treatment of cyanide poisoning, sodium thiosulfate acts as a sulfur donor, enabling the conversion of cyanide to thiocyanate, which is then excreted in urine. In calciphylaxis, it helps dissolve calcium deposits in blood vessels, improving circulation.
PACKAGING & DOSAGE
One pack contains 10 vials.
Active ingredient: Sodium thiosulfate 300 mg.
Excipients: Water for injection (for IV use), sodium chloride (as a stabilizer), pH adjusters.
Cyanide Poisoning (antidote) – Intravenous (IV) Use: Adults: 12.5 g IV (50 mL of a 25% solution) administered over 10–30 minutes. Children: 400 mg/kg (max 12.5 g) IV over 10–30 minutes. Often given with sodium nitrite for enhanced detoxification.Calciphylaxis (Severe Vascular Calcification in Kidney Disease) – Intravenous (IV) UseAdults: 12.5–25 g IV three times per week (after dialysis if applicable). Administered over 30–60 minutes to reduce adverse effects like nausea and hypotension. Chemotherapy Extravasation for adults: 2 mL of 0.17 M sodium thiosulfate injected subcutaneously for every 100 mg of cisplatin extravasated. Tinea Versicolor (Fungal Skin Infection), topical use: Dilute 25% sodium thiosulfate solution in water and apply directly to affected skin, followed by rinsing. Cyanide Poisoning: Adults: 4–10 g orally every 8 hours, depending on severity.
SIDE EFFECTS AND PRECAUTIONS
- Nausea & vomiting.
- Headache & dizziness.
- Hypotension (low blood pressure).
- Fluid overload (in IV use, especially in kidney disease patients).
- Allergic reactions (rare).
- Metabolic acidosis (in high doses).
- Use with caution in renal impairment.
- Sodium thiosulfate can cause hypotension.
- Individuals allergic to sodium thiosulfate should not use it.
STORAGE
Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.
QUESTIONS?
Ask us any questions about Sodium Thiosulfate.
