PREDNISOLONE (Orapred, PediaPred, Millipred) is a type of product known as a corticosteroid or steroid. Corticosteroids are not the same as anabolic steroids. Prednisolone is used to treat a wide range of health problems including allergies, blood disorders, skin diseases, infections, certain cancers and to prevent organ rejection after a transplant. It helps by reducing inflammation. It also damps down your immune system, which can help in autoimmune illnesses like rheumatoid arthritis, where your immune system mistakenly attacks its own tissues.

USES

• Treat certain types of allergies.
• Inflammatory conditions.
• Autoimmune disorders.
• Adrenocortical insufficiency.
• High blood calcium.
• Rheumatoid arthritis.
• Dermatitis.
• Eye inflammation.
• Asthma.
• Multiple sclerosis.

GUARANTEE & EXPIRY DAY
100% original from various Russian manufacturers including Obnovlenie PFK, Gedeon Richter RUS, Biosynthes, Synthes and others. Product photo may vary and is for illustration purpose only. Expiry date up to 10.2029.

DESCRIPTION
Prednisolone is a man-made form of a natural substance (corticosteroid hormone) made by the adrenal gland. Prednisone is a strong anti-inflammatory steroid and jack-of-all-trades. Prednisone mimics cortisol, your body’s “fight-or-flight” hormone. Cortisol’s many responsibilities include keeping inflammation at bay. “When we use prednisone as a treatment, we’re usually trying to either reduce inflammation directly or moderate the body’s inflammatory response,” says Dr. Ford.

Prednisolone works by mimicking the effects of cortisol, a hormone produced naturally by the adrenal glands. It reduces inflammation by decreasing the activity of the immune system, thereby providing relief from symptoms like swelling, redness, and allergic reactions. It is used in conditions such as rheumatoid arthritis, lupus, ulcerative colitis, asthma, and severe allergies, and also to manage adrenal insufficiency.

More specific, Prednisolone acts on glucocorticoid receptors to regulate the expression of anti-inflammatory proteins and suppress pro-inflammatory genes. This reduces the migration of immune cells to sites of inflammation and decreases the production of chemicals that cause inflammation. It influences carbohydrate, protein, and fat metabolism, maintaining homeostasis during stress. It also plays a role in suppressing the immune system to prevent tissue damage.

Benefits:

• Rapidly reduces inflammation and immune-mediated symptoms

• Controls allergic reactions and asthma exacerbations

• Supports hormone replacement in adrenal insufficiency

• Reduces symptoms and progression of autoimmune diseases.

The dose of Prednisolone and the duration of treatment are set by the doctor individually, depending on the indications and the severity of the disease.
In acute adrenal insufficiency, a single dose of Prednisolone is 100-200 mg, daily 300-400 mg.
For severe allergic reactions, Prednisolone is administered in a daily dose of 100-200 mg for 3-16 days.
In bronchial asthma, the drug is administered, depending on the severity of the disease and the effectiveness of complex treatment, from 75 to 675 mg for a course of treatment from 3 to 16 days; in severe cases, the dose can be increased to 1400 mg per course of treatment or more with a gradual dose reduction.
In status asthmaticus, Prednisolone is administered at a dose of 500–1200 mg per day, followed by a decrease to 300 mg per day and a transition to maintenance doses.

STORAGE
It is recommended to store Prednisolone in a dark place at a temperature not exceeding 25°C.

QUESTIONS
Ask us any questions about Prednisolone.