PAPAVERINE (Pavabid) is used as a smooth muscle relaxant. It is derived from the opium poppy but is non-narcotic and works differently from opioids.
USES
- Peripheral Vascular Diseases
- Cerebral Vasospasm
- Erectile Dysfunction
- Gastrointestinal Spasms
- Biliary and Urinary Tract Spasms
- Coronary Artery Spasm (Angina)
- Antispasmodic in Surgical Procedures
- Pulmonary Hypertension
GUARANTEE & EXPIRY DATE
100% original from various Russian pharmaceutical manufacturers. Product photo may vary.
All packs are air tight sealed and expire up to 06.2028.
DESCRIPTION
Papaverine Hydrochloride works by inhibiting phosphodiesterase enzymes, leading to increased levels of cyclic AMP (cAMP) and cyclic GMP (cGMP). This causes the relaxation of smooth muscles, particularly in blood vessels, improving blood flow and reducing spasms.
Papaverine is intended for the treatment of various ailments. It contains the active substance papaverine hydrochloride, which has an antispasmodic effect on the smooth muscles of organs. Papaverine is used to treat severe abdominal pain, vascular spasms, pain in neuralgia, gastric ulcer, cholecystitis, as well as other diseases associated with decreased smooth muscle tone. Papaverine is available in tablet form and injection, each tablet contains 40 mg of papaverine hydrochloride.
Papaverine works by relaxing the smooth muscles in the blood vessels of the penis, leading to increased blood flow, which can help achieve and maintain an erection. It does this by inhibiting enzymes that regulate smooth muscle contraction (such as phosphodiesterases), allowing the blood vessels to expand.
Papaverine is also available as a rectal suppository. Used to treat spasms of the smooth muscles of the abdominal organs. They contain the active substance papaverine hydrochloride, which helps to relax the muscles, eliminating spasms and pain in the gastrointestinal tract, urinary and female organs. Suppositories are easily inserted into the rectum and are quickly absorbed, starting to act a few minutes after use. Read further:
https://en.wikipedia.org/wiki/Papaverine
PACKAGING & DOSAGE
Strength: 40 mg/tab, 20 mg/suppository and 40 mg/mL for injections.
Package: Tablets 40mg, rectal suppositories 20mg, injections 40 mg/vial, 10 vials (intravenous, intramuscular, subcutaneous).
Active ingredients: Papaverine.
The dosage of Papaverine varies depending on the condition being treated, the patient's response, and the method of administration (oral or injectable). Below are the typical dosage guidelines:
Oral/Tablets dosage (Peripheral Vascular Disorders & Gastrointestinal Spasms):
Dose: 100 mg to 300 mg.
Frequency: 3 to 5 times daily.
Intravenous or Intramuscular injection (Peripheral Vascular Disorders & Cerebral Vasospasm):
Dose: 30 mg to 120 mg.
Frequency: Every 3 to 4 hours, as needed.
Administration: Injected slowly to prevent hypotension.
Intracavernosal Injection (for Erectile Dysfunction):
Dose: 10 mg to 80 mg.
Frequency: Administered only once every 24 hours.
SIDE EFFECTS
Papaverine Hydrochloride can cause a range of side effects, from mild to severe. The risk and severity of side effects depend on the dose, method of administration (oral, intravenous, or intracavernosal), and individual health conditions. These are usually mild and may go away as the body adjusts to treatment:
- Dizziness or lightheadedness
- Flushing
- Nausea or vomiting
- Sweating
- Blurred vision
- Headache
- Constipation
STORAGE
Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.
QUESTIONS?
Ask us any questions about Papaverine.
