OXYPROGESTERONE CAPROATE (Hydroxyprogesterone caproate, Proluton, Makena) in olive or peach oil, 12.5%, 1 ml/vial, 10 vials per pack

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OXYPROGESTERONE CAPROATE (Hydroxyprogesterone caproate, Proluton, Makena) is form of a female hormone that prevents preterm delivery. It is a form of progestin. The preparation including the hormone is taken to diminish the risks of premature birth. It is usually prescribed to women who had problems of this kind in the past and there is some reason for this appointment. The goal of use is to prevent premature labor.


  • Decreases excitability of the uterus and fallopian tubes.
  • Lowers contractility of the muscles of the uterus.
  • Helps to avoid premature birth.

100% original from Russian Dalhimpharm. Expiry date up to 12.2024.

It’s worth mentioning that progestogens can be divided into natural and synthetic. The difference is in the structure. If the structure of natural compounds repeats the structure of living organisms, the synthetic ones are generated artificially in the lab and undergo the modification of the structure. As a result, these types are absolutely different.

Oxyprogesterone is produced by the corpus luteum and then the placenta. It features a chemical structure that plays a key role in the support of pregnancy. This medication is analogue of hormone but it has different chemical composition because of a caproic acid residue. Its metabolism is slower than that of progesterone and, consequently, produces a more durable effect. It presents the properties that resemble the properties of the natural hormone. Binding to receptors on the surface of cells, it penetrates the nucleus for the activation of DNA and stimulation of RNA synthesis.

Oxyprogesterone comes in the form of injections with the solution in olive or peach oil. The medication contains the active substance Oxyprogesterone caproate. The preparation is injected into the muscle or under the skin. The first injection of the medicine is usually made in the second trimester of pregnancy. After the initial dose, one injection a week should be made as the effect of the injection can last from 7 to 14 days.

Store it at a room temperature. Do not exceed storage temperature higher than 25 degrees Celsius. Keep away from direct sunlight. Keep locked and away from children.

Ask us any questions about OXYPROGESTERONE CAPROATE.


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