Description
SIROLIMUS (Rapamycin) is characterized primarily by its ability to suppress the immune system, has anti-cancer and life extension properties. Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug’s name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.
USES
- Immunosuppressant.
- Anti-cancer properties.
- Coronary stent coating.
- Lymphangioleiomyomatosis.
- Vascular malformations.
- Angiofibromas.
GUARANTEE & EXPIRY DAY
100% original from the Indian Zydus. Expiry date up to 10.2029. Product photo may vary.
DESCRIPTION
Rapamycin's primary mechanism of action is the inhibition of the mammalian target of rapamycin (mTOR), which is a serine/threonine-specific protein kinase that regulates cell growth, proliferation, and survival. mTOR is an important therapeutic target for various diseases, as it was shown to regulate longevity and maintain normal glucose homeostasis. Targeting mTOR received more attention especially in cancer, as mTOR signalling pathways are constitutively activated in many types of human cancer.
Further read: https://en.wikipedia.org/wiki/Sirolimus
PACKAGE & DOSAGE
Sirolimus comes in the form of tablets.
Active ingredient: Rapamycin 1 mg.
Excipients: Sucrose, lactose monohydrate, polyethylene glycol, calcium sulfate, microcrystalline cellulose, pharmaceutical glaze, talc, titanium dioxide, magnesium stearate, povidone, poloxamer, glyceryl monooleate, carnauba wax, vitamin E (alpha-tocopherol acetate).
Usually 2 mg/day orally for transplant; 2-3 mg weekly for longevity; loading doses possible.
- Mouth ulcers, diarrhea, abdominal pain, high blood lipids, anemia, high blood pressure, increased risk of infections, and elevated liver enzymes.
- Sirolimus increases the risk of infections, including serious and opportunistic infections, as well as cancers such as lymphoma and skin cancer. Close monitoring for signs of infection and malignancy is essential.
STORAGE
The medicine must be stored at room temperature. Keep away from children and pet animals.
QUESTIONS
Ask us any questions about Sirolimus.