LYDASE (Hyaluronidase) breaks down the main component of the interstitial substance of connective tissue - hyaluronic acid, reduces its viscosity, increases tissue and vascular permeability, facilitates the movement of fluids in interstitial spaces; reduces tissue swelling, softens and flattens scars, increases the range of motion in the joints, reduces contractures and prevents their formation. Hyaluronidase causes the breakdown of hyaluronic acid to glucosamine and glucuronic acid and thereby reduces its viscosity. The duration of action for intradermal administration is up to 48 hours.

USES

• Burns, traumatic postoperative scars, long-term non-healing ulcers.
• Dupuytren's contracture; joint stiffness, joint contractures (after inflammatory processes, injuries), osteoarthritis, ankylosing spondylitis, severe diseases of the lumbar discs; chronic tendovaginitis, scleroderma (skin manifestations), hematoma of soft tissues of superficial localization; preparation for skin and plastic surgery for cicatricial contractions.
• Pulmonary tuberculosis (complicated by non-specific bronchial lesions), inflammatory processes in the upper respiratory tract and bronchi with obstruction symptoms.
• Traumatic lesions of the nerve plexuses and peripheral nerves (plexitis, neuritis).
• Hyphema, hemophthalmus, retinopathy of various etiology.

GUARANTEE & EXPIRY DAY
Original from the Russian Microgen NPO.
All packs are air tight sealed and expire up to 02.2026.

DESCRIPTION
Hyaluronidase are a family of enzymes that catalyse the degradation of hyaluronic acid (HA). Karl Meyer classified these enzymes in 1971, into three distinct groups, a scheme based on the enzyme reaction products.[1] The three main types of hyaluronidases are two classes of eukaryotic endoglycosidase hydrolases and a prokaryotic lyase-type of glycosidase.

PACKAGING & DOSAGE
Active ingredient: Hyaluronidase - 128 IU per ampoule.

In case of cicatricial lesions, subcutaneous tissue (under the scar tissue) or intramuscularly (near the lesion site), 64 IU (1 ml) is injected daily or every other day (only 10-20 injections).

In case of traumatic lesions of the nerve plexuses and peripheral nerves, inject s / c into the area of ​​the affected nerve (64 IU in Novocaine solution) every other day; per course - 12-15 injections. Repeat the course of treatment if necessary.

When used in ophthalmic practice, the contents of the vial are dissolved in 20 ml of water for injection (0.1% solution). The drug is administered subconjunctivally - 0.3 ml, parabulbar - 0.5 ml, as well as by electrophoresis.

STORAGE
The drug should be stored in a dark place, out of the reach of children, at a temperature not exceeding 15 degrees Celcius.

QUESTIONS
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