AZATHIOPRINE is an immunosuppressant that is primarily used to decrease the activity of the immune system in various autoimmune conditions and to prevent organ transplant rejection.

USES
Organ Transplantation:

• To prevent rejection after kidney, liver, and heart transplants. It helps to suppress the immune system to prevent the body from attacking the transplanted organ.

Autoimmune Diseases:

• Rheumatoid Arthritis: Used in patients with moderate to severe rheumatoid arthritis when other treatments are not effective.
• Systemic Lupus Erythematosus (SLE): Used to treat lupus-related kidney issues or other severe manifestations.

Crohn’s Disease: To manage inflammation in the intestines, particularly in severe cases.

• Ulcerative Colitis: For managing inflammation in the colon.
• Autoimmune Hepatitis: To suppress immune activity in the liver.

Other Conditions:

• Dermatomyositis and Polymyositis: Conditions involving muscle inflammation.
• Vasculitis: For inflammation of blood vessels.

GUARANTEE & EXPIRY DATE
100% original from the Russian OZON pharmaceuticals. All packs are air tight sealed and expire up to 06.2028.

DESCRIPTION
Azathioprine is used for the treatment of rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus; and in kidney transplants to prevent rejection. It is listed by the International Agency for Research on Cancer as a group 1 human carcinogen. It is taken by mouth or injected into a vein. Read further: https://en.wikipedia.org/wiki/Azathioprine

PACKAGING & DOSAGE
Azathioprine comes in tablets of 50 mg dosage.
Active ingredient: azathioprine - 50 mg.
Excipients: lactose monohydrate (milk sugar) - 108.76 mg; corn starch - 18.00 mg; calcium stearate - 1.80 mg; crospovidone - 0.90 mg; gelatin - 0.54 mg.

For Organ Transplantation:

• Initial Dose: Typically 3–5 mg/kg of body weight per day. The dose may be adjusted based on the individual’s response and tolerability.
• Maintenance Dose: After the initial phase, the dose is usually reduced to 1–3 mg/kg per day.

For Autoimmune Diseases:

• Rheumatoid Arthritis: The usual dose is 1–3 mg/kg/day, starting at a low dose and gradually increasing based on response.
• Systemic Lupus Erythematosus: Starting dose is usually around 1–2 mg/kg/day, with dose adjustments based on clinical response.
• Crohn’s Disease / Ulcerative Colitis: The dose typically ranges from 1–2.5 mg/kg/day.

For Children and Special Populations:

• The dosage for children and individuals with kidney or liver impairments is generally lower and requires careful monitoring.
  

SIDE EFFECTS

• Nausea and vomiting
• Diarrhea
• Fatigue
• Loss of appetite

STORAGE
Azathioprine should be stored at room temperature (typically 15–25°C or 59–77°F), in a dry place, away from sunlight and children.

QUESTIONS?
Ask us any questions about Azathioprine.