ARIFINE (Aripiprazole) is an atypical antipsychotic medication primarily used to treat mental health conditions. It works by balancing brain chemicals dopamine and serotonin, which affect mood and thought processes.
USES
Schizophrenia.
Bipolar disorder (acute manic and mixed episodes, maintenance).
Major depressive disorder (adjunctive treatment).
Irritability in autism spectrum disorder.
Tourette’s disorder.
GUARANTEE & EXPIRY DATE 100% original from various Indian pharmaceutical manufacturers. Product photo may vary. All packs are air tight sealed and expire up to 02.2028.
DESCRIPTION
Arifine (Aripiprazole) is a versatile atypical antipsychotic medication used mainly to treat schizophrenia, bipolar disorder, depression adjunctively, autism-related irritability, and Tourette's disorder. It balances brain dopamine and serotonin to improve symptoms with a generally favorable side effect profile compared to older antipsychotics.
Arifine (Aripiprazole) is a second-generation (atypical) antipsychotic. It modulates dopamine and serotonin receptors, acting as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors while antagonizing 5-HT2A receptors. This unique action contributes to symptom relief with fewer motor and metabolic side effects compared to first-generation antipsychotics.
Benefits:
Reduces psychotic symptoms such as hallucinations and delusions.
Controls mood swings in bipolar disorder.
Decreases irritability in autism.
Improves cognitive function and reduces some side effects such as tardive dyskinesia and cardiovascular risks in patients relative to older antipsychotics.
May restore sexual function and reduce alcohol cravings in dependent patients.
One package contains 30 tabs available in 10, 15 and 30 mg.
Active ingredient: Aripiprazole 10, 15 or 30 mg depending of the stength.
Excipients: Lactose monohydrate, croscarmellose sodium, hydroxypropyl cellulose, magnesium stearate, microcrystalline, indigo carmine and iron oxides.
Dosage:
Schizophrenia (adults): Start with 10-15 mg once daily. Most patients improve on 15 mg daily. Dosage can be increased up to 30 mg/day if needed. Dose adjustments should be spaced every 2 weeks.
Bipolar Mania (adults): Initial dose is usually 15 mg once daily, which can be increased to a maximum of 30 mg/day. When given with lithium or valproate, 10-15 mg/day is typical.
Adjunctive treatment for Major Depressive Disorder: Starting dose of 2-5 mg/day, gradually increasing to 5-15 mg/day.
Irritability associated with Autism (pediatric 6 to 17 years): Start at 2 mg/day, increase gradually to 5-15 mg/day.
Tourette’s Disorder (pediatric 6 to 18 years): Start at 2 mg/day for patients under 50kg and 2 mg/day escalating to 5-10 mg/day for those over 50kg, with possible increase to 20 mg/day.
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SIDE EFFECTS AND PRECAUTIONS
Headache, nausea, vomiting, dizziness, constipation, blurred vision. These side effects often improve over time as the body adjusts.
Avoid alcohol to reduce sedation and symptom worsening. Not recommended during pregnancy and breastfeeding unless benefits outweigh risks
STORAGE Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.
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